Isocyanide Synthase (ICS)
Biosynthetic Gene Clusters (BGC)
in the Fungal Kingdom

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2023

Nucleic Acids Research

Mining for a New Class of Fungal Natural Products

The Evolution, Diversity, and Distribution of Isocyanide Synthase Biosynthetic Gene Clusters across the fungal kingdom. Analysis of 1,329 fungal genomes revealing widespread ICS BGC diversity.

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2026 In Press

Current Biology

ICS BGCs in Lichenized Fungi

A deeper dive into isocyanide BGC clusters found in Lecanoromycetes. Includes updated crmA pathway analysis and characterization of four novel Lichen-Forming Fungi (LFF) ICS clades.

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